![]() ![]() After passing through several optical components, the raw beam creates an expanded, collimated beam that illuminates particles in the scattering volume. The process begins with a light source that generates a monochromatic beam. Typical schema of a laser diffraction instrument and major functions of each element Additionally, non-laser light sources are often used to complement the main laser source to gain additional characteristic information about submicron-size particles. General approaches are now based on the Mie theory and the measurement of scattering intensity over a wide scattering angular range is employed. Today, laser diffraction analyzers go beyond simple diffraction effects. Initially, particle sizing by laser diffraction was limited to the use of the Fraunhofer diffraction theory. Over the past two decades, laser diffraction has replaced conventional methods, such as sieving and sedimentation to size particles smaller than a few millimeters, and has replaced optical and electron microscopy for larger particles (>50 µm). ![]() Laser diffraction offers a number of advantages, including ease-of-use, fast operation, high reproducibility and broad dynamic size range-spanning almost five orders of magnitude, from nanometers to millimeters. This is an absolute method that doesn’t require calibration. Laser diffraction measurements capture information about particle size distribution by measuring scattering intensity as a function of the scattering angle, wavelength and polarization of light based on applicable scattering models. Liquid Handling and Scheduling Software.CytExpert Software for the CytoFLEX Platform.Plate Loader Options for the CytoFLEX Platform.CytoFLEX Violet-Blue-Red Series Upgrades.Labware for Liquid Handling Instruments.Biomek NGeniuS Reaction Vessel, 24 Well, 64/Box.Lysing, Fixative, and Permeabilizating Reagents.RESOURCE Contract Manufacturing Services.HIAC 9703+ Pharmaceutical Particle Counter.Biomek NGeniuS Next Generation Library Prep System.Cell Counters, Sizers and Media Analyzers.Air Particle Counters for Cleanroom and Environmental Monitoring.See more publications with ParticleTrack. A continuous multi-stage mixed-suspension mixed-product-removal crystallization system with fines dissolution, Acevedo et al., Chemical Engineering Research and Design, Volume 135, July 2018, Pages 112-120.Development and Scale-Up of a Crystallization Process To Improve an API’s Physiochemical and Bulk Powder Properties, Durak et al., Org.Characterization of a Multistage Continuous MSMPR Crystallization Process assisted by Image Analysis of Elongated Crystals, Capellades et al., Cryst.On-line observation of the crystal growth in the case of the non- typical spherical crystallization methods of ambroxol hydrochloride, Gyulai et al., Powder Technology, Volume 336, August 2018, Pages 144-149.Diastereomeric Salt Crystallization of Chiral Molecules via Sequential Coupled-Batch Operation, Simon et al., AIChE Journal, Volume 65, Issue 8. doi.org/10.1002/aic.16635.Diastereomeric Salt Crystallization of Chiral Molecules via Sequential Coupled-Batch Operation, Simon et al., AIChE Journal, Volume 65, Issue 8. doi.org/10.1002/.Effect of a polymer binder on the extraction and crystallization- based recovery of HMX from polymer-bonded explosives, Kim et al., Journal of Industrial and Engineering Chemistry, Volume 79, 25 November 2019, Pages 124-130. doi.org/10.1016/j.jiec.2019.06.014.Seed Recipe Design for Batch Cooling Crystallization with Application to L-Glutamic Acid, Zhang et al., Ind.The selection of journal articles below utilize particle size analyzers to address measuring solubility and metastable zone, crystallization design, seeding crystallization processes, optimizing crystal shape, monitoring supersaturation, polymorphic crystallization, phase separation (oiling out), managing impurities, crystallization scale-up, and continuous crystallization. ![]()
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